Sir William Vaughan attended Jesus College Oxford (B.A. 1595, M.A. 1597, B.C.L. 1600) and studied law on the Continent (L.L.D Vienna). He was sheriff of Carmarthen (1615) and was the chief undertaker of a plantation in Newfoundland. A supporter of Essex, Vaughan was a friend of the radical Protestant writers Thomas Scott and George Wither. He published under the pseudonym "Orpheus Junior."
Canticum canticorum Salomonis. 1597.
Erotopainion pium. 1598.
Poematum libellus. 1598.
The golden grove moralized in three books. 1600.
Naturall and artificial directions for health. 1600.
The spirit of detraction conjured and convicted. 1611.
Cambrensium Caroleia, by Orpheus Junior. 1625.
The golden fleece transported from Cambrioll Colchios, by Orpheus Junior. 1626.
The newlanders cure. 1630.
The Church Militant from the yeare 33 untill 1640. 1640.
The soules exercise in the daily contemplation of our Saviours birth, life, passion, and resurrection. 1641.