The son of George Gayton of London, Edmund Gayton studied at Merchant Taylors' School and St. John's College Oxford (B.A. 1629, M.A. 1633, Fellow, 1633, B.Med. 1648). He was a beadle in arts and medicine (1636-48). Gayton was in debtor's prison in 1655; he briefly succeeded Taylor the Water Poet as poet to the City of London before his death at Oxford.
Pleasant notes on Don Quixot. 1654.
Charity triumphant, or the virgin-shew, exhibited. 1655.
Hymnus de febribus. 1655.
Wil Bagnol's ghost in his perambulation of the prisons of London. 1655.
Wit revived. 1656.
The art of longevity, or, a diatecticall institutive. 1659.
To the most illustrious Prince his Highness James, Duke of York. 1661?
The religion of a physician; or divine meditations. 1663.
The glorious and living cinque-ports of our fortunate isle. 1666.