Little is known of William Chamberlayne, the second son of Warder Chamberlayne of Hindon. He was a Royalist who fought at the second battle of Newbury and who practiced medicine at Shaftesbury, Dorsetshire. His fantastic romance, Pharonnida, was admired by Robert Southey and no doubt influenced, in addition to the acknowledged imitation in Joan of Arc, some of the wilder scenes in Southey's later narrative poetry.
Loves victory: a tragi-comedy. 1658.
Pharonnida: an heroic poem. 1659.
England's jubilee, or a poem on the happy return of his sacred majesty Charles the Second. 1660.
Eromena: or, the noble stranger. A novel [by Chamberlayne?]. 1683.