The son of a musician, George Jeffreys attended Westminster School, the Middle Temple (1694), and Trinity College Cambridge (M.A. 1702; Fellow, 1701-09). He was secretary to the Bishop of Derry and a member of the household of his wealthy kinsman, the Duke of Chandos. Jeffreys composed the New Year's Ode for 1719 for Nicholas Rowe. An epistle from William Duncombe to George Jeffreys is reprinted in John Nichols's Select Collection (1780-84) 6:23-25.
Edwin: a tragedy. 1724.
Merope: a tragedy [after Maffei]. 1731.
Father Francis and sister Constance: a poem from a story in the Spectator; and Chess: a poems translated into English from Vida. 1736.
Miscellanies in prose and verse. 1754.