Pattison was the son of a farmer, and was sent by his father's landlord, the Earl of Thanet, to Appleby School, where he proved wild and idle and got into debt. He subsequently went to Sidney College, Cambridge, and being threatened with expulsion, left the university about 1726, and commenced author in London. In the pamphlet which was written by Savage under the name of Iscariot Hackney, and which is believed to have been instigated by Pope, it is said that "poor Pattison" was starved by Curll. It would have been nearer the truth to have said that Curll saved him from starving. He gave the young man shelter when he was penniless, and he died of small-pox in the house of the bookseller on the 10th of July, 1727, at the age of 21. Pattison, we are told, "earnestly solicited a friendship with Mr. Pope;" he certainly dedicated one of his poems to him, and Pope's name appears amongst the subscribers to his works.